Anguish See also Affliction; Distress; Grief; Persecution; Sorrow; Suffering; Tribulation; Trouble hearkened not unto Moses for anguish of spirit, Ex. 6:9. Trouble and anguish shall make him afraid, Job 15:24. Trouble and anguish have taken hold on me, Ps. 119:143. Tribulation and anguish, upon every soul of man, Rom. 2:9. out of much affliction and anguish of heart, 2Â Cor. 2:4. my soul is rent with anguish, 1Â Ne. 17:47. fill his breast with guilt, and pain, and anguish, Mosiah 2:38 (3:7). they were filled with pain and anguish, Mosiah 25:11. most bitter pain and anguish of soul, Alma 38:8. indignation, wailing, and anguish, D&C 124:52.