Vexation See also Trouble Lord shall send upon thee cursing, vexation, Deut. 28:20. all is vanity and vexation of spirit, Eccl. 1:14 (2:11, 17, 26; 6:9). hands full with travail and vexation of spirit, Eccl. 4:6. howl for vexation of spirit, Isa. 65:14. remnants … shall vex the Gentiles with a sore vexation, D&C 87:5.